|
| |
Research behind the effectiveness of
Corti+
EssentraTM Research:
The active ingredient in
Corti+
is Essentra. Currently, Essentra' s effectiveness is being evaluated in
a human study that will be submitted for publication. Additional research supporting Essentra's effectiveness
comes from studies performed by Dr. S. Ghosal in India. These studies provide excellent evidence of Essentra's effectiveness. For example,
 | Rats were treated with a stress-increasing
chemical, PTZ, with or without Essentra and then placed in a bright, noisy (stressfull)
environment. Control rats got neither PTZ or Essentra. The incidence of
defecation and urination was the measure of stress.
 | Control rats (stressful environment, no Essentra,
no PTZ): 10% stress-induced defecation, 30% stress-induced urination.
|
| Group A (stressful environment, only PTZ):
90% stress-induced defecation, 100% stress-induced urination. |
| Group B (stressful environment, PTZ plus
Essentra): 20% stress-induced defecation, 40% stress-induced urination. |
|
| Rats was forced to swim in inescapable containers
for six minutes. When rats “give up” under stress, they cease vigorous
swimming and hang motionless in the water, with their noses just above water.
The stress-induced immobility period for the control rats was 188 seconds, but
only 122 seconds for the Essentra-treated rats. |
| Rats were restrained in order to induce stress
ulcers. All of the control rats (no Essentra) got ulcers while only 20% of the
Essentra-treated rats got ulcers. |
| Rats were exposed to severe overcrowding
conditions, and then given morphine. All of the control rats (no
Essentra) developed convulsions while only 10% of the Essentra-treated rats
developed convulsions. |
| Rats were exposed to tactile stress (continuous
poking), and then given morphine. 70% of the control rats (no Essentra)
developed convulsions while only 10% of the Essentra-treated rats developed
convulsions. |
| Rats were restrained in order to induce
stress-related changes to the adrenal glands. Stress causes the adrenal glands
to enlarge and their content of vitamin C and corticosterone to drop (corticosterone
is the rat equivalent of cortisol). Vitamin C is used up in making
corticosterone and the corticosterone is released in response to stress
| Control rats (no restraint, no Essentra) average
adrenal gland weight was 25.4 mg/100 gms body weight, 298 mcg vitamin C/100
mg adrenal weight, and 3.9 mcg corticosterone/100 mg adrenal weight.
|
| Group A (restraint, no Essentra) average adrenal
gland weight was 34.2 mg/100 gms body weight, 126 mcg vitamin C/100 mg
adrenal weight, and 1.4 mcg corticosterone/100 mg adrenal weight.
|
| Group B (restraint plus Essentra) average adrenal
gland weight was 22.5 mg/100 gms body weight, 272 mcg vitamin C/100 mg
adrenal weight, and 4.4 mcg corticosterone/100 mg adrenal weight.
|
|
Other rat studies have shown that Essentra can
| Increase immune activity, |
| Increase learning and memory under stressful
conditions, |
| Increase the brain antioxidant enzymes SOD,
catalase, and glutathione peroxidase, and |
Ashwagandha
Research:
Other evidence for the effectiveness of
Corti+ comes from reports of
ashwagandha's traditional use in middle-eastern medicine (Ayurvedic medicine), from experimental studies in animals,
and a few clinical studies. Researchers believe that ashwagandha's effectiveness
is likely due to a modulation of cortisol metabolism
during periods of high stress. During stress, elevated cortisol levels can lead
to anxiety, suppressed immune system and thyroid function, and mental
decline.
|
Animal studies: Ashwagandha has shown benefits in treating anxiety, boosting immune system function, stimulation of thyroid function, and improvement in memory and
mental function.
|
|
Double blind clinical studies:
|
Ashwagandha was equal to or better than ginseng in improving
problem-solving ability, reaction time and physical performance under the
applied experimental conditions. |
|
Ashwagandha slowed the process of aging as evaluated in
certain parameters such as rate of calcium loss
in nails, red blood cell count and sex-drive. |
|
Order Corti+:
References for information contained
on this page
|
